Ocular Cytopathology

An atlas that features the cytologic findings of the normal features and diseases of the eye.

About Mission for Vision

Friday, September 30, 2005

Ch 7. Eales Disease of the Retina

EALES’ DISEASE

Eales’ disease was initially described in young males with vitreous hemorrhage and abnormal retinal veins.[59] Now it is clinically defined by an obliterative vasculopathy involving both venules and arterioles (Figure 7-9).[60] In the late stages, ischemia leads to neovascularization with resulting vitreous hemorrhage, retinal detachment, and secondary glaucoma.[61][62] Specimens are obtained when vitrectomy is done to remove persistent vitreous hemorrhage or extraretinal fibrous tissue.[63] Cytologic specimens may show vitreous hemorrhage (hemoglobin spherulosis) and, occasionally, fibrous tissue (Figure 7-10).
Other conditions that produce neovascularization and vitreous hemorrhage include branch retinal vein occlusion,[64] sickle cell retinopathy,[65] carotid and aortic arch occlusive syndromes,[66] and hyperviscosity syndromes.[67]
References:
59. Eales H. Cases of retinal hemorrhage associated with epistaxis and constipation. Birm Med Rev 1880;9:262.
60. Elliot AJ. Thirty-year observation of patients with Eales' disease. Am J Ophthalmol 1975;80:404-408.
61. Renie WA, Murphy RP, Anderson KC, Lippman SM, McKusick VA, et al. The evaluation of patients with Eales' disease. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1975;194:73-85.
62. Spitznas M, Meryer-Schwickerath GT, Staphan B. The clinical picture of Eales' disease. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1975;194:73-85.
63. Gieser SC, Murphy RP. Eales' disease. In: Ryan SJ, Schachat AP, Murphy RP, Patz A, eds. Retina. St. Louis: C.V. Mosby, 1989;2:535-540.
64. Heyreh SS, Rojas P, Podhajsky P, Montague P, Woolson RF. Ocular neovascularization with retinal vein occlusion. Ophthalmology 1983;20:488-506.
65. Goldberg MF. Classifcation and pathogenesis of proliferative sickle retinopathy. Am J Ophthalmol 1971;71:649-665.
66. Kahn M, Green WR, Knox DL, MIller NR. Ocular features of carotid occlusive disease. Retina 1986;6:239-252.
67. Ring CP, Pearson TC, Sanders MD, Wetherly Mein G. Viscosity and retinal vein thrombosis. Br J Ophthalmol 1967;60:397-410.



0 Comments:

Post a Comment

<< Home