Morphology and Behavior of Tumors

Dysplasia, Neoplasms, Cancer, Staging, Differentiation

• 1. Define differentiation. What is the difference between well-differentiated and poorly-differentiated cancer cells?


• 2. Differentiate dysplasia from cancer.


• 3. Define tumor.


• 4. What is a neoplasm?


• 5. Compare the rate of growth in benign and malignant neoplasms.


• 6. Compare invasion in benign and malignant tumors.


• 7. What is metastasis and how does it define a tumor?


• 8. What are the routes of metastatic spread?


• 9. What is the difference between tumor grade and tumor stage?


• 10. Describe dysplasia.


• 11. Compare carcinoma versus sarcoma.


• 12. State the correct terminology for: a) benign glandular tumor b) malignant


• glandular tumor c) benign mesenchymal tumor of fat d) malignant mesenchymal


• tumor of fat


• 13. Define the features that are indicative of malignancy.


• 14. Define the features that are indicative of benignity (neoplasm).


• 15. Define the terms, pleomorphism, and anaplasia.


• 16. What is the significance of abnormal mitotic figures being present in neoplasm?


• 17. Compare a stage I malignant neoplasm with a stage IV malignant neoplasm.


• 18. What are features that relate to architectural abnormalities in histologic section ?


• 19. What are features that relate to cytologic abnormalities in histologic section ?