Study Guide for dental students and dentists

This is a comprehensive study guide for dental students and dentists. On this site you will Histology of the Human Eye for UCLA Dental Students. In addition there is a comprehensive study guide for the Systemic Pathology.

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Saturday, September 24, 2005

Wound Healing

Non-specific wound healing (general concepts); Specific Wounds, Healing by Primary and Secondary Intention.

  • 1. Describe the sequence of events in non-specific wound healing, and provide a related time table.

  • 2. Define wound contraction.

  • 3. Define wound strengthening.

  • 4. Compare and contrast abrasion from incision/laceration.

  • 5. Describe a wound with epidermal defects.

  • 6. Which substances are elaborated, and by which cells (i.e., collagen types, fibronectin, etc)?

  • 7. Compare temporary matrix composition vs. definitive matrix composition.

  • 8. List the cells, and cell components involved in wound contraction. Provide a time frame of events.

  • 9. What is the tensile strength of the wound at time points 1 week, and 3 months?

  • 10. Compare the tensile strength of various collagens.

  • 11. Describe the time course of healing of a sutured skin wound.

  • 12. Compare the processes of primary vs. secondary intention in terms of inflammation, necrosis, cellular proliferation, and scar formation.

  • 13. What are the events of healing following bone fracture?

  • 14. What are the growth factors involved in wound healing?

  • 15. List the local and systemic factors that interfere with wound healing.

  • 16. Define pyogenic granuloma and keloid, and describe their morphologic features in histologic sections.

  • 17. What is the role of matrix metalloprocesses in wound healing?

  • 18. Name a few diseases and factors that interfere with healing.


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